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2026 International Prophylaxis Study Group (IPSG) Virtual Symposium

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    Eastern Daylight Time; 3:30 PM CEST; 8:30 PM ICT

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"Revisiting Non-Factor Therapies"

Itinerary

09:30

Welcome & Introduction

Co-Moderators: Prof. Dr. Karin Fijnvandraat1 / Dr. Rungrote Natesirinilkul2


  • Brief overview of the webinar goals
  • Introduction of speakers
  • Housekeeping (Q&A format, chat rules, recording info)

1Professor of Pediatric Hematology at the University of Amsterdam; Director of the Hemophilia Treatment Center Amsterdam.
2Assistant Professor, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Thailand.

09:35

Integrating therapies for prophylaxis

Johnny Mahlangu, MD, PhD

Evolving Paradigm in Haemophilia Management: Integrating SHL FVIII, EHL FVIII, Ultra-Long FVIII, and Non-Factor Therapies: Prophylactic strategies
Haemophilia Comprehensive Care Centre, Charlotte Maxeke Johannesburg Hospital and Professor and Head, Department of Molecular Medicine and Haematology NHLS and University of the Witwatersrand, Johannesburg

09:55

Surgery under non-factor therapies

Giancarlo Castaman, M.D.

Head, Center for Bleeding Disorders and Coagulation, Department of Heart, Lung and Vessels, Careggi University Hospital, Italy

10:15

Efficacy measurement in non-factor therapies

Alfonso Iorio, MD, PhD

Professor and Chair, Department of Health Research Methods, Evidence, and Impact (HEI)
McMaster University; Director of the Health Information Research Unit (HiRU, and the Hamilton-Niagara Hemophilia Program, Canada

10:35

Panel Discussion (Q&A)

Panelists: Karin Fijnvandraat, Rungrote Natesirinilkul, Johnny Mahlangu, Giancarlo Castaman, Alfonso Iorio

Panel Discussion (Q&A)

11:00

Closing Remarks

Co-Moderators: Prof. Dr. Karin Fijnvandraat / Dr. Rungrote Natesirinilkul

2026 International Prophylaxis Study Group (IPSG) Virtual Symposium

Meet Your Speakers

Karin Fijnvandraat
Co-Moderator

Karin Fijnvandraat


Karin Fijnvandraat is Professor of Pediatric Hematology at the University of Amsterdam and Director of the Hemophilia Treatment Center Amsterdam. She trained in Pediatrics and specialized in Pediatric Hematology at the University of Amsterdam. Her clinical focus is on hemophilia, allied bleeding disorders and sickle cell disease. In 2007 she initiated the international INSIGHT Consortium to enhance collaboration on non-severe hemophilia research among 34 hemophilia treatment centers in 10 European countries and Australia. Her research in hemophilia focusses on phenotypic heterogeneity and inhibitor development in mild hemophilia A. Furthermore, she contributed to many multicenter studies in hemophilia, von Willebrand disease, neonatal transfusion and sickle cell disease.

Rungrote Natesirinilkul
Co-Moderator

Rungrote Natesirinilkul


Dr. Rungrote Natesirinilkul had spent two years training in hemostasis at the Hospital for Sick Children at the University of Toronto, prior to accepting his position as an assistant professor at Chiang Mai University in Thailand. He actively attends national, regional and international meetings on hemostasis as well as hemophilia and has been exposed to knowledge on patient care in relation to prophylaxis and the particular barriers faced in Southeast Asia.

Johnny Mahlangu, MD
Speaker

Johnny Mahlangu, MD


Johnny Mahlangu is a Professor and Academic Head of the Department of Molecular Medicine and Haematology in the Faculty of Health Sciences of the University of the Witwatersrand and the National Health Laboratory Service. He is also a Consultant Clinical Haematologist at the Charlotte Maxeke Johannesburg Academic Hospital. Johnny received his undergraduate and postgraduate training in science and medicine at the University of the Witwatersrand with haematology specialist and clinical haematology sub-specialist qualifications through the Colleges of Medicine of South Africa. His main area of research is novel therapies in bleeding disorders, in which he has served as Principal Investigator for a large number of international multicentre studies. He has published many peer review journal articles and presented more than 500 oral talks and posters at national and international scientific meetings. His academic citizenship includes membership of many national and international Scientific Committees.

Giancarlo Castaman, M.D.
Speaker

Giancarlo Castaman, M.D.


Giancarlo Castaman is Director of the Center for Bleeding Disorders and Coagulation at Careggi University Hospital in Florence, Italy. He is currently serving as President of the Italian Society of Hemostasis and Thrombosis. Additionally, he is co-chair of the subcommittee of FVIII, FIX, and Rare Bleeding Disorders Group of the ISTH and chairs the Scientific Working Group on Bleeding and Thrombosis of the European Hematology Association (EHA). His publications include approximately 500 scientific papers, 800 abstracts and 40 chapters in scientific books.

Alfonso Iorio, MD, PhD, FRCP(C)
Speaker

Alfonso Iorio, MD, PhD, FRCP(C)


Alfonso Iorio is Professor and Chair, Department of Health Research Methods, Evidence, and Impact at McMaster University Canada. He is Director of the Health Information Research Unit (HiRU, http://hiru.mcmaster.ca/hiru) and of the Hamilton-Niagara Hemophilia Program. He received his medical and PhD degrees from the University of Perugia, Italy.

He is the Principal Investigator of the Web Application for Population Pharmacokinetic in Hemophilia (WAPPS) project (www.wapps-hemo.org), co-investigator of the Patient Reported Outcomes, Burden, and Experiences (PROBE), and Chair of the Canadian Bleeding Disorders Registry (CBDR). He is past-chair of the WFH Data and Demographics committee, and co-chair of the World Bleeding Disorders Registry (WBDR).

He is Associate Editor for bleeding disorders of the Cochrane Collaboration, Thrombosis Research, and serves on the Editorial Boards of numerous journals including the Journal of Thrombosis and Haemostasis, and Haemophilia.

Outside Hemophilia, his current research interests include internet-based knowledge dissemination, systematic review and meta-analysis methodology, risk prediction and stratification, and artificial intelligence application to all of them.

He has authored over 300 peer reviewed papers totaling over 20,000 citations and a H-index of 59 (details available on his personal page Google Scholar). He has given many lectures, including educational lectures at many international conferences.

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